S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Aft1p	YLR214W	PubMed Yamaguchi-Iwai Y et al., EMBO J, 1995 Mar 15;14(6):1231-9	Indirect	lacZ - wt vs TF overexpression	Positive	S288c	cells grown with iron deprivation, expressing a constitutive AFT1 allele
		PubMed Yamaguchi-Iwai Y et al., EMBO J, 1996 Jul 1;15(13):3377-84	Direct	EMSA	N/A	S288c	in vitro
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	N/A
		PubMed Courel M et al., Mol Cell Biol, 2005 Aug;25(15):6760-71	Indirect	Microarray WT vs TF mutant	Positive	Y14438	Iron-depleted conditions - Defined medium (iron-limiting and copper-limiting yeast nitrogen base ); 30.C.
			Indirect	Microarray analysis - wt vs TF mutant	Positive	SCMC01	Iron-depleted conditions - Defined medium (iron-limiting and copper-limiting yeast nitrogen base ); 30.C.
		PubMed Miao R et al., Biochemistry, 2011 Apr 5;50(13):2660-71	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	Iron depletion
			Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	iron repletion, constitutive TF