S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Crz1p	YDR040C	PubMed Matheos DP et al., Genes Dev, 1997 Dec 15;11(24):3445-58	Indirect	lacZ - wt vs TF overexpression	Positive	S288c	SC medium 50mM Ca2+
		PubMed Mendizabal I et al., FEBS Lett, 1998 Mar 27;425(2):323-8	Indirect	lacZ - wt vs TF mutant	Positive	S288c	Osmotic stress
		PubMed Yoshimoto H et al., J Biol Chem, 2002 Aug 23;277(34):31079-88	Indirect	Microarray analysis - wt vs TF mutant	Positive	DBY7286	Cells grown to log phase in YPD medium before being exposed to 0.2 M CaCl2 for 15 min
			Indirect	Microarray analysis - wt vs TF mutant	Positive	DBY7286	Cells grown to log phase in YPD medium before being exposed to 0.8 M NaCl for 30 min
		PubMed Serrano R et al., Mol Microbiol, 2002 Dec;46(5):1319-33	Indirect	lacZ - wt vs TF mutant	Positive	S288c	Alkaline pH stress; Cells cultivated in SC medium at pH 8
		PubMed Chua G et al., Proc Natl Acad Sci U S A, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h
		PubMed Wiesenberger G et al., Eukaryot Cell, 2007 Apr;6(4):592-9	Indirect	Northern blot - wt vs TF mutant	Positive	BY4741	Mg2+ starvation
		PubMed Ruiz A et al., J Biol Chem, 2008 May 16;283(20):13923-33	Direct	ChIP	N/A	S288c	Calcium-induced stress; Exponential-phase cells cultivated in YPD medium supplemented with 0.2 M CaCl2
		PubMed Cai L et al., Nature, 2008 Sep 25;455(7212):485-90	Indirect	GFP - wt vs TF overexpression	Positive	S288c	SC medium + increasing Calcium concentrations
		PubMed MarquÃ©s MC et al., FEMS Yeast Res, 2015 Jun;15(4):fov017	Indirect	Western blot - wt vs TF mutant	Positive	S288c	Strains treated with 0.5 M NaCl for 3 min harbouring a genomic integration of the GFP coding sequence at the ENA1 C-terminus.
		PubMed Roque A et al., BMC Genomics, 2016;():Roque A et al., BMC Genomics, 2016;():	Direct	ChIP-seq	N/A	S288c	YPD medium, pH 8.0 (alkaline stress)
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	YPD medium, 25.C