S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Fkh2p	YPR119W	PubMed Althoefer H et al., Mol Cell Biol, 1995 Nov;15(11):5917-28	N/A		N/A	S288c	N/A
		PubMed Madhani HD et al., Proc Natl Acad Sci U S A, 1999 Oct 26;96(22):12530-5	Direct	ChIP	N/A	S288c	Exponential phase cells cultivated in YPD growth medium
		PubMed Hollenhorst PC et al., Genetics, 2000 Apr;154(4):1533-48	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	YPD medium; mid-log phase
		PubMed Zhu G et al., Nature, 2000 Jul 6;406(6791):90-4	Direct	ChIP	N/A	W303	15, 30, 45, 60 min after release of G1 phase synchronization
			Indirect	Northern blot - wt vs TF mutant	N/A	W303	0-180 min after release of G1 phase synchronization
			Indirect	Microarray analysis - wt vs TF mutant	Positive	W303	15, 30, 45, 60 min after release of G1 phase synchronization
		PubMed Koranda M et al., Nature, 2000 Jul 6;406(6791):94-8	N/A		N/A	S288c	N/A
		PubMed Pic A et al., EMBO J, 2000 Jul 17;19(14):3750-61	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	cell cycle periodic activation
		PubMed Kumar R et al., Curr Biol, 2000;():Kumar R et al., Curr Biol, 2000;():	Indirect	lacZ - wt vs TF mutant	Positive	S288c	YPD medium; mid-log phase
		PubMed Simon I et al., Cell, 2001 Sep 21;106(6):697-708	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Lee TI et al., Science, 2002 Oct 25;298(5594):799-804	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Shapira M et al., Mol Biol Cell, 2004 Dec;15(12):5659-69	Indirect	Microarray analysis - wt vs TF mutant	N/A	S288c	N/A
		PubMed Pic-Taylor A et al., Mol Cell Biol, 2004 Nov;24(22):10036-46	Direct	ChIP	N/A	S288c	growth on galactose
		PubMed Workman CT et al., Science, 2006 May 19;312(5776):1054-9	Direct	Chip-on-chip	N/A	S288c	N/A
		PubMed Sherriff JA et al., Mol Cell Biol, 2007 Apr;27(8):2848-60	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	YPD medium; mid-log phase
		PubMed Voth WP et al., EMBO J, 2007 Oct 17;26(20):4324-34	Direct	ChIP	N/A	S288c	N/A
		PubMed Veis J et al., Mol Cell Biol, 2007 Dec;27(23):8364-73	Direct	ChIP	N/A	S288c	N/A
		PubMed Casey L et al., Mol Biol Cell, 2008 Feb;19(2):608-22	Indirect	Northern blot - wt vs TF mutant	Positive	W303-1A	wt vs TF mutant
		PubMed Pondugula S et al., Mol Cell Biol, 2009 Sep;29(18):4891-905	Direct	ChIP	N/A	S288c	YPD medium; mid-log phase
		PubMed Sekiya M et al., Genes Genet Syst, 2009 Aug;84(4):269-76	Indirect	Northern blot - wt vs TF mutant	Positive	YOC3191	fks1-1154 cells and fks1-1154 cells overexpressing FKH2 gene of each strain were incubated in YPGS (YPD with 2% galactose and 0.1% sucrose instead of 2% of glucose) at 25.C for 3h. G1 cells were isolated and cultured in YPGS containing 15 microh/mL nocodazole for 240min at 37.C
		PubMed Darieva Z et al., Mol Cell, 2010 Apr 9;38(1):29-40	Direct	ChIP	N/A	S288c	N/A
		PubMed Linke C et al., Front Physiol, 2013;():Linke C et al., Front Physiol, 2013;():	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	G2/M phase arrested cells
		PubMed Yelamanchi SK et al., Mol Cell Biol, 2014 Feb;34(4):711-24	Direct	ChIP	N/A	S288c	YPD
		PubMed Edenberg ER et al., Mol Cell Biol, 2014 Feb;34(4):725-38	Direct	ChIP	N/A	S288c	MMS
		PubMed Ostrow AZ et al., PLoS One, 2014;9(2):e87647	Direct	Chip-on-chip	N/A	S288c	Unspecified medium, 23.C, synchronized with alpha-factor, hydroxyurea or nocodazole
		PubMed Shi BJ, Biochem J, 2016 Nov 1;473(21):3855-3869	Direct	ChIP	N/A	S288c	Synchronous growth
		PubMed Linke C et al., NPJ Syst Biol Appl, 2017 Mar 6;3(1):	Direct	ChIP	Positive	BY4741	BY4741; YPD medium; 30.C; mid-log phase
			Indirect	RT-PCR - wt vs TF mutant	Positive	BY4741 fkh2DELTA	BY4741 fkh1DELTA; yeast cells treated with 5 microg/ml NOCODAZOLE; YPD medium; 30.C
			Indirect	RT-PCR - wt vs TF mutant	Positive	BY4741 fkh1DELTAfkh2DELTA	BY4741 fkh1DELTAfkh2DELTA; yeast cells treated with 5 microg/ml NOCODAZOLE; YPD medium; 30.C
			Indirect	RT-PCR - wt vs TF mutant	Positive	BY4741 fkh2DELTA	BY4741 fkh1DELTA; yeast cells treated with 75 mM Hydroxyurea; YPD medium; 30.C
			Indirect	RT-PCR - wt vs TF mutant	Positive	BY4741 fkh1DELTAfkh2DELTA	BY4741 fkh1DELTAfkh2DELTA; yeast cells treated with 75 mM Hydroxyurea; YPD medium; 30.C
		PubMed Sukegawa Y et al., J Cell Sci, 2018 Jul 9;131(13):jcs219063	Indirect	RT-PCR - wt vs TF mutant	Positive	S288C hog1DELTAfkh2DELTA	Strains with fks1 mutant allele (temperature-sensitive mutant); YPD medium; 37.C
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	YPD medium, 25.C