S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Gcn4p	YGR019W	PubMed Moxley JF et al., Proc Natl Acad Sci U S A, 2009 Apr 21;106(16):6477-82	Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4741	YNB media
		PubMed Staschke KA et al., J Biol Chem, 2010 May 28;285(22):16893-911	Indirect	lacZ - wt vs TF mutant	Negative	EG328-1A	yeast cells deleted for GCN4 and GLN3 were transformed with a plasmid encoding a lacZ reporter gene fused to the UGA1 promoter. Cells were cultured in synthetic medium containing ammonia as the nitrogen source and then switched to synthetic medium containing 10 mM GABA as the nitrogen source for 6 h
			Indirect	lacZ - wt vs TF mutant	Negative	EG328-1A	yeast cells deleted for GCN4 were transformed with a plasmid encoding a lacZ reporter gene fused to the UGA1 promoter. Cells were cultured in synthetic medium containing ammonia as the nitrogen source and then switched to synthetic medium containing 10 mM GABA as the nitrogen source for 6 h