S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Hap1p	YJR048W	PubMed Kim KS et al., Nature, 1989 Nov 9;342(6246):200-3	N/A		N/A	S288c	N/A
		PubMed Ramil E et al., Mol Microbiol, 2000 Sep;37(5):1116-32	Indirect	lacZ - wt vs TF mutant	Positive	S288c	Minimal medium with 0,1% glucose 2% ethanol 2% lactate
		PubMed Ter Linde JJ et al., Yeast, 2002 Jul;19(10):825-40	Indirect	Microarray analysis - wt vs TF mutant	Positive	CEN.PK113-7D	Steady-state chemostat cultures aerobically grown on mineral mediium containing 7.5 g/L glucose (growth-limiting nutrient)
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	N/A
		PubMed Hickman MJ et al., Mol Cell Biol, 2007 Nov;27(21):7414-24	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288C	wt versus hap1DELTA YPD mid-exp cells aerobic conditions
			Indirect	Microarray analysis - wt vs TF mutant	Negative	S288C	wt versus hap1DELTA YPD mid-exp cells anerobic conditions ( supplemented with ergosterol, tween 80 and ethanol)
		PubMed Morohashi N et al., Biol Pharm Bull, 2008 Feb;31(2):187-92	Direct	In vivo UV-photofootprinting	N/A	S288c	SC medium; mid-log phase
		PubMed Ihrig J et al., Eukaryot Cell, 2010 Mar;9(3):460-71	Indirect	Luciferase - wt vs mutant promoter sequence	Positive	S288c	50mM FeCl3
		PubMed Zhang T et al., J Biol Chem, 2017 Oct 13;292(41):16942-16954	Direct	ChIP	N/A	W303	hypoxic conditions
			Direct	ChIP	N/A	W303	YEP medium
		PubMed Bergenholm D et al., mSystems, 2018 Jul-Aug;3(4):	Direct	ChIP-exo	N/A	CEN.PK 113-5D	Steady state aerobic chemostat cultivation at 30 .C in nitrogen-limited minimal medium containing vitamins and trace metals and maintained at pH 5.0
			Direct	ChIP-exo	N/A	CEN.PK 113-5D	Steady state aerobic chemostat cultivation at 30 .C in glucose-limited minimal medium containing vitamins and trace metals and maintained at pH 5.0
			Direct	ChIP-exo	N/A	CEN.PK 113-5D	Steady state chemostat cultivation at 30 .C in oxygen- and glucose-limited minimal medium containing vitamins and trace metals and maintained at pH 5.0
			Direct	ChIP-exo	N/A	CEN.PK 113-5D	Steady state aerobic chemostat cultivation at 30 .C in ethanol-limited minimal medium containing vitamins and trace metals and maintained at pH 5.0
		PubMed Holland P et al., Nucleic Acids Res, 2019 Jun 4;47(10):4986-5000	Direct	ChIP-exo	N/A	CEN.PK 113-5D	Cells were cultivated in chemostats in anaerobic glucose limited medium with a dilution rate of 0.1 h-1 at 30.C. Samples were collected after steady state was achieved for 48-60 h
			Direct	ChIP-exo	N/A	CEN.PK 113-5D	Cells were cultivated in chemostats in ethanol limited medium with a dilution rate of 0.1 h-1 at 30.C. Samples were collected after steady state was achieved for 48-60 h
			Direct	ChIP-exo	N/A	CEN.PK 113-5D	Cells were cultivated in chemostats in nitrogen limited medium with a dilution rate of 0.1 h-1 at 30.C. Samples were collected after steady state was achieved for 48-60 h
			Direct	ChIP-exo	N/A	CEN.PK 113-5D	Cells were cultivated in chemostats in respiratory glucose limited medium with a dilution rate of 0.1 h-1 at 30.C. Samples were collected after steady state was achieved for 48-60 h
		PubMed Barba-Aliaga M et al., Int J Mol Sci, 2020 Dec 28;22(1):	Indirect	RT-PCR - wt vs. TF mutant	Positive	BY4741	SC medium 7 h