S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Met4p	YGR087C	PubMed Cormier L et al., Nucleic Acids Res, 2010 Aug;38(15):4998-5014	Direct	ChIP	N/A	W303	Isogenic strain expressing Myc-tagged Met4 was grown to early log phase in YPD medium and exposed to 0.5 mM Cd2+. Binding to PDC6 upstream region (from -455 to -306 relative to ATG)
			Direct	ChIP	N/A	W303	Isogenic strain expressing Myc-tagged version of Met4 was grown to early log phase in YPD medium and exposed to 0.5mM Cd2+.
			Indirect	RT-PCR - wt vs TF mutant	Positive	W303	Met4 hyperactivation: met4::GAL1-MET4 DELTAmet30 cells were grown in YP-raffinose medium to early logphase and supplemented or not with galactose
			Indirect	RT-PCR - wt vs TF mutant	Positive	W303	wt vs DELTAmet4: cells were grown to early log phase in YPD medium and exposed to 0.5 mM Cd2+