S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Msn2p	YBR126C	PubMed Parrou JL et al., Microbiology, 1997;():	Indirect	lacZ - wt vs TF mutant	Positive	S288c	37ºC
		PubMed Boy-Marcotte E et al., J Bacteriol, 1998 Mar;180(5):1044-52	Indirect	Proteomics - wt vs TF mutant	Positive	W303	YNB medium
		PubMed Boy-Marcotte E et al., Mol Microbiol, 1999 Jul;33(2):274-83	Indirect	Proteomics - wt vs TF mutant	Positive	W303-A	Heat-shock: Exponential-phase cells shifted from 25C to 38C
		PubMed Rep M et al., J Biol Chem, 2000 Mar 24;275(12):8290-300	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	YPD + 0,5M NaCl
		PubMed Hasan R et al., Mol Microbiol, 2002 Jul;45(1):233-41	Indirect	Proteomics - wt vs TF mutant	Positive	YPH98	Oxidative stess; cells grown in YNB medium to exponential phase exposed to 0.5 mM H2O2 for 30 min
		PubMed Hasan R et al., Mol Microbiol, 2002 Jul;45(1):233-41	Indirect	2D electrophoresis (WT vs msn2DELTAmsn4DELTAyap1DELTA triple mutant)	Positive	YPH98	Oxidative stess; cells grown in YNB medium to exponential phase exposed to 0.5 mM H2O2 for 30 min
		PubMed Kandror O et al., Mol Cell, 2004 Mar 26;13(6):771-81	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	Cold stress; Cells cultivated for 24h at 0ºC in YP growth medium with galactose as carbon source
		PubMed Lai LC et al., Mol Cell Biol, 2005 May;25(10):4075-91	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	SSGal-TEA medium + anaerobiosis (0,19 generations)
		PubMed Chua G et al., Proc Natl Acad Sci U S A, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h
		PubMed Berry DB et al., Mol Biol Cell, 2008 Nov;19(11):4580-7	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	YPD+0.5 mM H2O2
			Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	YPD+0.7 M NaCl 45min
		PubMed Capaldi AP et al., Nat Genet, 2008;():Capaldi AP et al., Nat Genet, 2008;():	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	YPD medium containing 0,8M glucose (glucose "osmotic" stress)
		PubMed Hazelwood LA et al., Appl Environ Microbiol, 2009 Nov;75(21):6876-85	Indirect	Microarray analysis - wt vs TF mutant	Positive	IMZ066	Nitrogen-limiting (45 g/L glucose, 1 g/L (NH4)2SO4, 5.3 g/L K2SO4, 3 KH2PO4, 0.5 g/L MgSO4.7H2O, 0.0045 g/L ZnSO4.7H2O)
		PubMed Watanabe D et al., Appl Environ Microbiol, 2011 Feb;77(3):934-41	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	Sake mash on day 5
		PubMed Casado C et al., Biochem J, 2011 Sep 15;438(3):523-33	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	10 min shift to pH=8
		PubMed Huebert DJ et al., Mol Cell Biol, 2012 May;32(9):1645-53	Direct	Chip-on-chip	N/A	S288c	H2O2 treatment
		PubMed Sasano Y et al., Biosci Biotechnol Biochem, 2012;():	Direct	RT-PCR - wt vs mutant promoter sequence	Positive	S288c	YPD medium; mid-log phase
		PubMed Stewart-Ornstein J et al., Curr Biol, 2013 Dec 2;23(23):2336-45	Indirect	GFP - wt vs TF overexpression	Positive	S288c	Estradiol induced
		PubMed Elfving N et al., Nucleic Acids Res, 2014 May;42(9):5468-82	Indirect	Microarray analysis - wt vs TF overexpression	Positive	S288c	SD + glucose + estradiol induction