S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Ste12p	YDR461W	PubMed Dolan JW et al., Proc Natl Acad Sci U S A, 1989 Aug;86(15):5703-7	Direct	EMSA	N/A	S288c	YPD medium; mid-log phase
		PubMed Fields S et al., Mol Cell Biol, 1988 Feb;8(2):551-6	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	N/A
		PubMed Madhani HD et al., Proc Natl Acad Sci U S A, 1999 Oct 26;96(22):12530-5	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	haploid-invasive growth conditions; Haploid cells grown in YPD rich medium
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Chua G et al., Proc Natl Acad Sci U S A, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h
		PubMed Heise B et al., Eukaryot Cell, 2010 Apr;9(4):514-31	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	SC medium; mid-log phase
		PubMed Chavel CA et al., PLoS Genet, 2010 Mar 19;6(3):e1000883	Indirect	Microarray analysis - wt vs TF mutant	Positive	SIGMA1278b	wt and DELTAste12 cells cells containing an activated allele of MSB2 were grown in YEP-GAL for 6h, at which point cells were examined by microscopy for the characteristic filamentation response
			Indirect	Microarray analysis - wt vs TF mutant	Positive	SIGMA1278b	wt and DELTAste12 cells cells overexpressing the MSB2 gene were grown in YEP-GAL for 6h, at which point cells were examined by microscopy for the characteristic filamentation response