S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Ste12p	YFL026W	PubMed Hwang-Shum JJ et al., Mol Gen Genet, 1991 Jun;227(2):197-204	Direct	EMSA	N/A	S288c	in vitro
		PubMed Errede B et al., Genes Dev, 1989 Sep;3(9):1349-61	Direct	EMSA	N/A	S288c	in vitro
		PubMed Fields S et al., Mol Cell Biol, 1988 Feb;8(2):551-6	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	N/A
		PubMed Oehlen LJ et al., Mol Cell Biol, 1996 Jun;16(6):2830-7	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	15mg/mL nocodazole
		PubMed Madhani HD et al., Proc Natl Acad Sci U S A, 1999 Oct 26;96(22):12530-5	Indirect	Microarray analysis - wt vs TF mutant	Negative	S288c	Pseudohyphal growth conditions (4h of growth in yeast nitrogen base containing 50 Î¼M ammonium sulfate)
		PubMed Lee TI et al., Science, 2002 Oct 25;298(5594):799-804	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Zeitlinger J et al., Cell, 2003 May 2;113(3):395-404	Direct	Chip-on-chip	N/A	S288c	N/A
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Chua G et al., Proc Natl Acad Sci U S A, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h
		PubMed Zheng W et al., Nature, 2010 Apr 22;464(7292):1187-91	Direct	ChIP-seq	N/A	S288c	YPD medium + alpha-factor
		PubMed Chavel CA et al., PLoS Genet, 2010 Mar 19;6(3):e1000883	Indirect	Microarray analysis - wt vs TF mutant	Positive	SIGMA1278b	wt and DELTAste12 cells cells containing an activated allele of MSB2 were grown in YEP-GAL for 6h, at which point cells were examined by microscopy for the characteristic filamentation response
		PubMed Chow J et al., Genetics, 2019 Jul;212(3):667-690	Indirect	RNA-seq - wt vs TF mutant	Positive	PC538	YEP-Gal solid medium for 24 hr
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	YPD medium, 25.C