S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Ste12p	YLR042C	PubMed Madhani HD et al., Proc Natl Acad Sci U S A, 1999 Oct 26;96(22):12530-5	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	haploid-invasive growth conditions; Haploid cells grown in YPD rich medium
		PubMed Chua G et al., Proc Natl Acad Sci U S A, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h
		PubMed LefranÃ§ois P et al., BMC Genomics, 2009;():	Direct	ChIP-seq	N/A	S288c	Pseudohyphal growth conditions (nitrogen depleted SLAD medium)
		PubMed Pitoniak A et al., Mol Biol Cell, 2009 Jul;20(13):3101-14	Indirect	lacZ - wt vs TF mutant	Positive	S288c	YPGal medium; mid-log phase
		PubMed Zheng W et al., Nature, 2010 Apr 22;464(7292):1187-91	Direct	ChIP-seq	N/A	S288c	YPD medium + alpha-factor
		PubMed Chavel CA et al., PLoS Genet, 2010 Mar 19;6(3):e1000883	Indirect	Microarray analysis - wt vs TF mutant	Positive	SIGMA1278b	wt and DELTAste12 cells cells containing an activated allele of MSB2 were grown in YEP-GAL for 6h, at which point cells were examined by microscopy for the characteristic filamentation response
			Indirect	Microarray analysis - wt vs TF mutant	Positive	SIGMA1278b	wt and DELTAste12 cells cells overexpressing the MSB2 gene were grown in YEP-GAL for 6h, at which point cells were examined by microscopy for the characteristic filamentation response
		PubMed Chow J et al., Genetics, 2019 Jul;212(3):667-690	Indirect	RNA-seq - wt vs TF mutant	Positive	PC538	YEP-Gal solid medium for 24 hr
		PubMed Vandermeulen MD et al., PLoS Genet, 2022 Jan;18(1):e1009988	Indirect	RT-PCR - wt vs. TF mutant	Positive	PC538	YPD 5h, 30.
			Indirect	RT-PCR - wt vs. TF mutant	Positive	PC538	YPGAL 5h, 30.C