Transcription Factor |
Target ORF/Genes |
References |
Evidence Code |
Evidence Experiment |
Association Type |
Strain |
Environmental Condition |
Yap1p
|
YJR104C
|
PubMed
Lee J et al., J Biol Chem, 1999 Jun 4;274(23):16040-6Lee J et al., J Biol Chem, 1999 Jun 4;274(23):16040-6 |
Indirect |
Proteomics - wt vs TF mutant |
Positive |
S288c |
15 minutes exposure to 0.2 mM H2O2 (SC growth medium) |
PubMed
Dumond H et al., Mol Microbiol, 2000 May;36(4):830-45Dumond H et al., Mol Microbiol, 2000 May;36(4):830-45 |
Indirect |
Microarray analysis - wt vs TF mutant |
Positive |
W303a |
Exponential cells grown in galactose minimal medium followed by oxidative stress (0.4mM H2O2) |
PubMed
Lee TI et al., Science, 2002 Oct 25;298(5594):799-804Lee TI et al., Science, 2002 Oct 25;298(5594):799-804 |
Direct |
Chip-on-chip |
N/A |
S288c |
YPD medium; mid-log phase |
PubMed
Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104 |
Direct |
Chip-on-chip |
N/A |
S288c |
YPD medium; mid-log phase |
PubMed
Haugen AC et al., Genome Biol, 2004;5(12):R95Haugen AC et al., Genome Biol, 2004;5(12):R95 |
Indirect |
Microarray analysis - wt vs TF mutant |
Positive |
BY4741 |
Synthetic complete medium after 2h exposure to 100 microM AsIII (30.C). |
PubMed
Lucau-Danila A et al., Mol Cell Biol, 2005 Mar;25(5):1860-8Lucau-Danila A et al., Mol Cell Biol, 2005 Mar;25(5):1860-8 |
Direct |
ChIP |
N/A |
S288c |
YPD medium + 20 mg/L benomyl |
PubMed
Dubacq C et al., Mol Genet Genomics, 2006 Feb;275(2):114-24Dubacq C et al., Mol Genet Genomics, 2006 Feb;275(2):114-24 |
Indirect |
Microarray analysis - wt vs TF mutant |
Positive |
S288c |
YPD medium + 200mM hydroxyurea |
PubMed
Thorsen M et al., Physiol Genomics, 2007 Jun 19;30(1):35-43Thorsen M et al., Physiol Genomics, 2007 Jun 19;30(1):35-43 |
Indirect |
Microarray analysis - wt vs TF mutant |
Positive |
W303-1A |
1.0 mM As(III), 1 h |
PubMed
Tan K et al., Proc Natl Acad Sci U S A, 2008 Feb 26;105(8):2934-9Tan K et al., Proc Natl Acad Sci U S A, 2008 Feb 26;105(8):2934-9 |
Direct |
Chip-on-chip |
N/A |
S288c |
SC medium + MMS (methylmethanesulfonate) |
PubMed
Menezes RA et al., Biochem J, 2008 Sep 1;414(2):301-11Menezes RA et al., Biochem J, 2008 Sep 1;414(2):301-11 |
Indirect |
RT-PCR - wt vs TF mutant |
Positive |
BY4741 |
2mM Na2HAsO or NaAsO2 |
PubMed
Salin H et al., BMC Genomics, 2008 Jul 15;0(0):33Salin H et al., BMC Genomics, 2008 Jul 15;0(0):33 |
Direct |
Chip-on-chip |
N/A |
BY4742 |
YPD + Sodium selenite (1 mM), hydrogen peroxide (0.3 mM) or benomyl (20 microg/ml) |
Indirect |
Microarray analysis - wt vs TF mutant |
Negative |
BY4742 |
YPD |
Indirect |
Microarray analysis - wt vs TF mutant |
Negative |
BY4742 |
YPD+1mM selenite 40 min |
Indirect |
Microarray analysis - wt vs TF mutant |
Negative |
BY4742 |
YPD+1mM selenite 60 min |
Indirect |
Microarray analysis - wt vs TF mutant |
Negative |
BY4742 |
YPD+1mM selenite 80 min |
PubMed
Kelley R et al., PLoS Genet, 2009 May;5(5):e1000488Kelley R et al., PLoS Genet, 2009 May;5(5):e1000488 |
Indirect |
Microarray analysis - wt vs TF mutant |
Positive |
BY4741 |
YPD 30.C 0.1 mM H2O2 |
PubMed
Reimand J et al., Nucleic Acids Res, 2010 Aug;38(14):4768-77Reimand J et al., Nucleic Acids Res, 2010 Aug;38(14):4768-77 |
Indirect |
Microarray analysis - wt vs TF mutant |
Positive |
S288c |
YPD medium; mid-log phase |
PubMed
Bleoanca I et al., J Biosci Bioeng, 2013 Dec;116(6):697-705Bleoanca I et al., J Biosci Bioeng, 2013 Dec;116(6):697-705 |
Indirect |
RT-PCR - wt vs TF mutant |
Positive |
S288c |
SC medium + EtOH 7.5% |
PubMed
Pimentel C et al., Biochim Biophys Acta, 2014 Jun;1840(6):1977-86Pimentel C et al., Biochim Biophys Acta, 2014 Jun;1840(6):1977-86 |
Indirect |
RT-PCR - wt vs TF mutant |
Positive |
S288c |
2 mM CoSO4 |
PubMed
Zhang C et al., Yeast, 2016 Jan;33(1):5-19Zhang C et al., Yeast, 2016 Jan;33(1):5-19 |
Indirect |
RNA-seq - wt vs TF mutant |
Positive |
S288c |
SD medium + t-BHP + MMS |
PubMed
da Silva SM et al., Biochim Biophys Acta Gen Subj, 2018 Oct;1862(10):2152-2161da Silva SM et al., Biochim Biophys Acta Gen Subj, 2018 Oct;1862(10):2152-2161 |
Indirect |
Microarray analysis - wt vs TF mutant |
Positive |
BY4741 |
YPD + 2 mM arsenic |
PubMed
Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314 |
Direct |
ChIP-exo |
N/A |
BY4741 |
YPD medium, 25.C |