S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Yap1p	YKL086W	PubMed Cohen BA et al., Mol Biol Cell, 2002 May;13(5):1608-14	Indirect	lacZ - wt vs TF mutant	Positive	BY4740	Oxidative stress; cells grown in SD medium in the presence of 0.6 mM H2O2 for 1 h
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	N/A
		PubMed Haugen AC et al., Genome Biol, 2004;5(12):R95	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	Synthetic complete medium after 2h exposure to 100 microM AsIII (30.C).
		PubMed Dubacq C et al., Mol Genet Genomics, 2006 Feb;275(2):114-24	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	YPD medium + 200mM hydroxyurea
		PubMed Horan S et al., Yeast, 2006 May;23(7):519-35	Indirect	Microarray analysis - wt vs TF mutant	Positive	W303-1B	Cells harvested 60 min after treatment with 3 mM NO donor (Z)-1-[2-(2-aminoethyl)-N-(2-ammonioethyl) aminodiazen-1-ium-1,2-diolate (DETA NONOate)
		PubMed Salin H et al., BMC Genomics, 2008 Jul 15;0(0):33	Direct	Chip-on-chip	N/A	BY4742	YPD + Sodium selenite (1 mM), hydrogen peroxide (0.3 mM) or benomyl (20 microg/ml)
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 40 min
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 60 min
		PubMed Fujiwara H et al., Mitochondrion, 2013 Jan;13(1):52-8	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	100% O2
		PubMed Pimentel C et al., Biochim Biophys Acta, 2014 Jun;1840(6):1977-86	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	2 mM CoSO4
		PubMed Zhang C et al., Yeast, 2016 Jan;33(1):5-19	Indirect	RNA-seq - wt vs TF mutant	Positive	S288c	SD medium + MMS
		PubMed da Silva SM et al., Biochim Biophys Acta Gen Subj, 2018 Oct;1862(10):2152-2161	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	YPD + 2â€¯mM arsenic