S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Yap1p	YKR076W	PubMed DeRisi JL et al., Science, 1997 Oct 24;278(5338):680-6	Indirect	Microarray analysis - wt vs TF overexpression	Positive	S288c	Exponential-phase cells cultivated in YPD supplemented with 2% galactose to induce protein expression
		PubMed Haugen AC et al., Genome Biol, 2004;5(12):R95	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	Synthetic complete medium after 2h exposure to 100 microM AsIII (30.C).
		PubMed Lucau-Danila A et al., Mol Cell Biol, 2005 Mar;25(5):1860-8	Indirect	Microarray analysis - wt vs TF mutant	N/A	S288c	N/A
		PubMed Dubacq C et al., Mol Genet Genomics, 2006 Feb;275(2):114-24	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	YPD medium + 200mM hydroxyurea
		PubMed Barreto L et al., Eukaryot Cell, 2006 Oct;5(10):1748-59	Indirect	Northern blot - wt vs TF mutant	Positive	W303-1A	Cells were grown in SC medium until a concentration of 1.5E07 cells per mL then 5 microg/mL CdCl2 was added and samples obtained after 30 min.
			Indirect	Northern blot - wt vs TF mutant	Positive	W303-1A	Cells were grown in SC medium until a concentration of 1.5E07 cells per mL then 5 microg/mL CdCl2 was added and samples obtained after 60 min.
			Indirect	Northern blot - wt vs TF mutant	Positive	W303-1A	Cells were grown in YPD medium until a concentration of 1.5E07 cells per mL then 0.2 mM 1-chloro-2,4-dinitrobenzene (CDNB) was added and samples obtained after 30 min.
			Indirect	Northern blot - wt vs TF mutant	Positive	W303-1A	Cells were grown in YPD medium until a concentration of 1.5E07 cells per mL then 0.2 mM 1-chloro-2,4-dinitrobenzene (CDNB) was added and samples obtained after 60 min.
			Indirect	Northern blot - wt vs TF mutant	Positive	W303-1A	Cells were grown in YPD medium until a concentration of 1.5E07 cells per mL then 1 mM t-BOOH was added and samples obtained after 30 min.
			Indirect	Northern blot - wt vs TF mutant	Positive	W303-1A	Cells were grown in YPD medium until a concentration of 1.5E07 cells per mL then 1 mM t-BOOH was added and samples obtained after 60 min.
			Indirect	Northern blot - wt vs TF mutant	Positive	W303-1A	Cells were grown in YPD medium until a concentration of 1.5E07 cells per mL then 2.5 mM diamide was added and samples obtained after 30 min.
			Indirect	Northern blot - wt vs TF mutant	Positive	W303-1A	Cells were grown in YPD medium until a concentration of 1.5E07 cells per mL then 2.5 mM diamide was added and samples obtained after 60 min.
		PubMed Salin H et al., BMC Genomics, 2008 Jul 15;0(0):33	Direct	Chip-on-chip	N/A	BY4742	YPD + Sodium selenite (1 mM), hydrogen peroxide (0.3 mM) or benomyl (20 microg/ml)
			Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4742	YPD
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 40 min
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 60 min
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 80 min
		PubMed Kelley R et al., PLoS Genet, 2009 May;5(5):e1000488	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	YPD 30.C 0.1 mM H2O2
		PubMed Kelley R et al., PLoS Genet, 2009 May;5(5):e1000488	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	YPD 30.C from 0.1 mM H2O2 to 0.4 mM H2O2
		PubMed Zhang C et al., Yeast, 2016 Jan;33(1):5-19	Indirect	RNA-seq - wt vs TF mutant	Positive	S288c	SD medium + t-BHP + MMS
		PubMed da Silva SM et al., Biochim Biophys Acta Gen Subj, 2018 Oct;1862(10):2152-2161	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	YPD + 2â€¯mM arsenic