S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Yap1p	YLL026W	PubMed Dumond H et al., Mol Microbiol, 2000 May;36(4):830-45	Indirect	Microarray analysis - wt vs TF mutant	Positive	W303a	Exponential cells grown in galactose minimal medium followed by oxidative stress (0.4mM H2O2)
		PubMed Hasan R et al., Mol Microbiol, 2002 Jul;45(1):233-41	Indirect	Proteomics - wt vs TF mutant	Positive	YPH98	Oxidative stess; cells grown in YNB medium to exponential phase exposed to 0.5 mM H2O2 for 30 min
		PubMed Lucau-Danila A et al., Mol Cell Biol, 2005 Mar;25(5):1860-8	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	YPD medium + 20 mg/L benomyl
		PubMed Chua G et al., Proc Natl Acad Sci U S A, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h
		PubMed Thorsen M et al., Physiol Genomics, 2007 Jun 19;30(1):35-43	Indirect	Microarray analysis - wt vs TF mutant	Positive	W303-1A	0.2 mM As(III), 1 h
		PubMed Tan K et al., Proc Natl Acad Sci U S A, 2008 Feb 26;105(8):2934-9	Direct	Chip-on-chip	N/A	S288c	SC medium + MMS (methylmethanesulfonate)
		PubMed Salin H et al., BMC Genomics, 2008 Jul 15;0(0):33	Direct	Chip-on-chip	N/A	BY4742	YPD + Sodium selenite (1 mM), hydrogen peroxide (0.3 mM) or benomyl (20 microg/ml)
			Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4742	YPD
			Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4742	YPD+1mM selenite 40 min
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 60 min
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 80 min
		PubMed Zhang C et al., Yeast, 2016 Jan;33(1):5-19	Indirect	RNA-seq - wt vs TF mutant	Positive	S288c	SD medium + t-BHP