S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Yap1p	YML007W	PubMed DeRisi JL et al., Science, 1997 Oct 24;278(5338):680-6	Indirect	Microarray analysis - wt vs TF overexpression	Positive	S288c	Exponential-phase cells cultivated in YPD supplemented with 2% galactose to induce protein expression
		PubMed Haugen AC et al., Genome Biol, 2004;5(12):R95	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	Synthetic complete medium after 2h exposure to 100 microM AsIII (30.C).
		PubMed Dubacq C et al., Mol Genet Genomics, 2006 Feb;275(2):114-24	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	YPD medium + 200mM hydroxyurea
		PubMed Workman CT et al., Science, 2006 May 19;312(5776):1054-9	Direct	Chip-on-chip	N/A	S288c	N/A
		PubMed Chua G et al., Proc Natl Acad Sci U S A, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h
		PubMed Salin H et al., BMC Genomics, 2008 Jul 15;0(0):33	Direct	Chip-on-chip	N/A	BY4742	YPD + Sodium selenite (1 mM), hydrogen peroxide (0.3 mM) or benomyl (20 microg/ml)
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 40 min
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 60 min
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 80 min
		PubMed Orumets K et al., Biotechnol J, 2012 Apr;7(4):566-8	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	glucose-limited chemostat
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	YPD medium, 25.C