S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Yap1p	YML028W	PubMed Lee J et al., J Biol Chem, 1999 Jun 4;274(23):16040-6	Direct	EMSA	N/A	S288c	in vitro
		PubMed Wong CM et al., J Biol Chem, 2002 Feb 15;277(7):5385-94	Indirect	lacZ - wt vs TF mutant	Positive	S288c	H2O2 treatment
		PubMed Hasan R et al., Mol Microbiol, 2002 Jul;45(1):233-41	Indirect	Proteomics - wt vs TF mutant	Positive	YPH98	Oxidative stess; cells grown in YNB medium to exponential phase exposed to 0.5 mM H2O2 for 30 min
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Haugen AC et al., Genome Biol, 2004;5(12):R95	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	Synthetic complete medium after 2h exposure to 100 microM AsIII (30.C).
		PubMed Lucau-Danila A et al., Mol Cell Biol, 2005 Mar;25(5):1860-8	Direct	ChIP	N/A	S288c	YPD medium + 20 mg/L benomyl
		PubMed Dubacq C et al., Mol Genet Genomics, 2006 Feb;275(2):114-24	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	YPD medium + 200mM hydroxyurea
		PubMed Workman CT et al., Science, 2006 May 19;312(5776):1054-9	Direct	Chip-on-chip	N/A	S288c	N/A
		PubMed Chua G et al., Proc Natl Acad Sci U S A, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Negative	N/A	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h
		PubMed Thorsen M et al., Physiol Genomics, 2007 Jun 19;30(1):35-43	Indirect	Microarray analysis - wt vs TF mutant	Positive	W303-1A	1.0 mM As(III), 1 h
		PubMed Tan K et al., Proc Natl Acad Sci U S A, 2008 Feb 26;105(8):2934-9	Direct	Chip-on-chip	N/A	S288c	SC medium + MMS (methylmethanesulfonate)
		PubMed Salin H et al., BMC Genomics, 2008 Jul 15;0(0):33	Direct	Chip-on-chip	N/A	BY4742	YPD + Sodium selenite (1 mM), hydrogen peroxide (0.3 mM) or benomyl (20 microg/ml)
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 40 min
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 60 min
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 80 min
		PubMed Kelley R et al., PLoS Genet, 2009 May;5(5):e1000488	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	YPD 30.C 0.1 mM H2O2
		PubMed Kelley R et al., PLoS Genet, 2009 May;5(5):e1000488	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	YPD 30.C from 0.1 mM H2O2 to 0.4 mM H2O2
		PubMed Reimand J et al., Nucleic Acids Res, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	YPD medium; mid-log phase
		PubMed Weiner A et al., PLoS Biol, 2012;10(7):e1001369	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	YPD medium; mid-log phase
		PubMed Pimentel C et al., Biochim Biophys Acta, 2014 Jun;1840(6):1977-86	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	2 mM CoSO4
		PubMed Zhang C et al., Yeast, 2016 Jan;33(1):5-19	Indirect	RNA-seq - wt vs TF mutant	Positive	S288c	SD medium + MMS
		PubMed Shedlovskiy D et al., J Biol Chem, 2017 Nov 10;292(45):18469-18485	Indirect	RT-PCR - wt vs TF mutant	Positive	BY4741	YPDA medium (1% yeast extract, 2% peptone, 2% dextrose, 10 mg/L adenine) treated with 0.2 mM H2O2 (oxidative stress) for 60, 120, 240 and 480 min
		PubMed da Silva SM et al., Biochim Biophys Acta Gen Subj, 2018 Oct;1862(10):2152-2161	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	YPD + 2â€¯mM arsenic
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	YPD medium, 25.C