Transcription Factor |
Target ORF/Genes |
References |
Evidence Code |
Evidence Experiment |
Association Type |
Strain |
Environmental Condition |
Zap1p
|
YGL255W
|
PubMed
Zhao H et al., Mol Cell Biol, 1997 Sep;17(9):5044-52Zhao H et al., Mol Cell Biol, 1997 Sep;17(9):5044-52 |
N/A |
|
N/A |
S288c |
N/A |
PubMed
Lyons TJ et al., Proc Natl Acad Sci U S A, 2000 Jul 5;97(14):7957-62Lyons TJ et al., Proc Natl Acad Sci U S A, 2000 Jul 5;97(14):7957-62 |
Indirect |
lacZ - wt vs TF overexpression |
Positive |
DY1457 |
Exponential cells grown in synthetic defined medium + zinc |
Indirect |
Microarray analysis - wt vs TF mutant |
Positive |
DY1457 |
Exponential cells grown in synthetic defined medium + zinc |
PubMed
Han GS et al., J Biol Chem, 2001 Mar 30;276(13):10126-33Han GS et al., J Biol Chem, 2001 Mar 30;276(13):10126-33 |
Indirect |
lacZ - wt vs TF mutant |
Positive |
S288c |
cells in zinc-deplete media (SD medium without zinc sulfate) weregrown to the exponential phase of growth (A600 nm ; 0.5) in the absence of zinc sulfate |
PubMed
Lee TI et al., Science, 2002 Oct 25;298(5594):799-804Lee TI et al., Science, 2002 Oct 25;298(5594):799-804 |
Direct |
Chip-on-chip |
N/A |
S288c |
YPD medium; mid-log phase |
PubMed
Bird AJ et al., EMBO J, 2004 Mar 10;23(5):1123-32Bird AJ et al., EMBO J, 2004 Mar 10;23(5):1123-32 |
Indirect |
Northern blot - wt vs TF mutant |
Positive |
S288c |
Zinc stress |
PubMed
Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104 |
Direct |
Chip-on-chip |
N/A |
S288c |
YPD medium; mid-log phase |
PubMed
Chua G et al., Proc Natl Acad Sci U S A, 2006 Aug 8;103(32):12045-50Chua G et al., Proc Natl Acad Sci U S A, 2006 Aug 8;103(32):12045-50 |
Indirect |
Microarray analysis - wt vs TF overexpression |
Positive |
N/A |
Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h |
PubMed
Wu CY et al., J Biol Chem, 2007 Jan 26;282(4):2184-95Wu CY et al., J Biol Chem, 2007 Jan 26;282(4):2184-95 |
Indirect |
Microarray analysis - wt vs TF mutant |
Positive |
S288c |
zinc depletion |
PubMed
Wu CY et al., BMC Genomics, 2008;():Wu CY et al., BMC Genomics, 2008;(): |
Direct |
DNA footprinting |
Positive |
S288c |
SD medium + 2% galactose + 1 μM ZnCl2 |
PubMed
Reimand J et al., Nucleic Acids Res, 2010 Aug;38(14):4768-77Reimand J et al., Nucleic Acids Res, 2010 Aug;38(14):4768-77 |
Indirect |
Microarray analysis - wt vs TF mutant |
Positive |
S288c |
YPD medium; mid-log phase |
PubMed
Frey AG et al., J Biol Chem, 2011 Feb 25;286(8):6844-54Frey AG et al., J Biol Chem, 2011 Feb 25;286(8):6844-54 |
Indirect |
lacZ - wt vs TF mutant |
Positive |
S288c |
LZM (Low Zinc Medium) + 3microM ZnCl2 |
PubMed
Toesca I et al., PLoS Genet, 2011 Jun;7(6):e1002163Toesca I et al., PLoS Genet, 2011 Jun;7(6):e1002163 |
Direct |
ChIP |
N/A |
S288c |
zinc depletion |
PubMed
Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314 |
Direct |
ChIP-exo |
N/A |
BY4741 |
YPD medium, 25.C |